In view of the fact that the Italian population is characterized by a progressive aging and that depression in old age represents a very widespread disorder, but often not recognized and adequately treated, it is considered worthwhile to know which therapies give evidence of effectiveness in contrasting the onset of this pathology, improving the elderly quality of life. The purpose of the following systematic review is to understand if the reminiscence therapy improves the geriatric patient’s mood and decreases his depression, becoming an efficient tool for the treatment of this psychopathology. The research carried out through the electronic databases
EBSCO and GOOGLE SCHOLAR, takes into account the articles from 2000 to 2019 selected by the following criteria: studies dealing with all kind of reminiscence therapy (instrumental and integrative); studies reporting depression as a major tested out-come; studies considering subjects > 60 years of age without a diagnosis of dementia or mild cognitive impairment; articles in English or Italian, article with available full text. The review seems to evidence that reminiscence therapy is an excellent option of treatment in case of senile depression that would lead to substantial symptoms alleviation.